PvM posted Entry 3046 on April 9, 2007 04:18 PM.
Trackback URL: http://www.pandasthumb.org/cgi-bin/mt/mt-tb.fcgi/3036

On UcD, Dembski shows such a level of despair about the lack of fertility of the ID thesis that he is willing to claim anything which mentions the word Darwin(ism) and problem(atic) as ID friendly. While Dembski provides, as usual, little more than a snippet introduction and fails to formulate much of anything similar to what could be considered an argument, I argue that his claim that the paper is pro-ID is lacking in logic, supporting evidence and relevance.

It is helpful to remind ourselves of what Intelligent Design is, free from its rhetoric and equivocation: “The set theoretic complement of chance and regularity”. In other words, that which cannot be explained by chance and regularity is given the label ‘intelligent design’. In this case we notice that the authors are talking about science exploring a better understanding of proteins (in other words regularities) as well as Darwinian approaches to design proteins (regularity and chance).

Here’s a pro-ID article without the usual disclaimers (e.g., a ritualistic suck-up to Darwin, an obligatory sneer at ID). Perhaps this is a sign of things to come.

Protein engineering: opportunities and challenges
Matti Leisola and Ossi Turunen

Journal Applied Microbiology and Biotechnology
SOURCE: http://www.springerlink.com/content/d514772515583767/

|Abstract: The extraordinary properties of natural proteins demonstrate that life-like protein engineering is both achievable and valuable. Rapid progress and impressive results have been made towards this goal using rational design and random techniques or a combination of both. However, we still do not have a general theory on how to specify a structure that is suited to a target function nor can we specify a sequence that folds to a target structure. There is also overreliance on the Darwinian blind search to obtain practical results. In the long run, random methods cannot replace insight in constructing life-like proteins. For the near future, however, in enzyme development, we need to rely on a combination of both.

Steve Reuland already defused much of the ‘claims’ made in a posting on PT called The Pro-ID Paper That Wasn’t. I intent to focus instead on the scientific irrelevance that is better known as “Intelligent Design”

I have already shown that the paper fails to have any relevance to the concept of Intelligent Design, so what about its weaker cousin “Teach the Controversy”, which is a thinly disguised attempt to introduce quote mining as ‘scientific evidence’, mostly against Darwinian theory? Again the paper fails to support this thesis, although it does make some arguments that indicate that Darwinian approaches may not be always successful when designing proteins. But that’s hardly a surprise.

Perhaps Dembski considers it ID friendly or pro-ID because at least one of the authors of the paper is a known creationist, strengthening the unavoidable link between religion and Intelligent design? Matti Leisola seems to be quite active in the creationist movement and was involved in inviting Paul Nelson and Richard von Sternberg to speak at the Helsinki University of Technology. And despite all this, we see little relevance to ID in this article. Is this the best ID has to offer I wonder? It should not come as a surprise that various people have argued convincingly that ID lacks scientific content, is scientifically vacuous and infertile?

Beyond the abstract

Since the paper is quite interesting, it may be helpful to venture beyond the abstract and see what the overall argument really is all about:

The argument is that there may be too much reliance on Darwinian approaches in designing new proteins, although the successes of Darwinian processes should not be ignored:

It is often said that random genetic methods to improve enzyme properties “rely on simple but powerful Darwinian principles of mutation and selection” (Johannes and Zhao 2006). We agree. It is also said that “every protein has become adapted by step-by-step improvement and refinement of its function over millions of years” (McLachlan 1987). The present theories, however, only partly explain the protein diversity, although a recent study (Poelwijk et al. 2007) shows that even the key-lock dilemma can be resolved by the Darwinian approach when the operation field for random search is within the same protein family, and the new key-lock pair closely resembles the original (ancestral).


In spite of the progress, we still do not have a general theory on how a sequence produces a specific structure and how a structure determines a function. Therefore, a blind Darwinian search within a known protein scaffold is often used to modify proteins. Unfortunately, blind searches have hard resource limits whereas insight has not. Therefore, in the long run, blind searches are of limited value in compensating our present ignorance. We still have a long way to go before we are able to design a suitable protein scaffold, position binding, and catalytic groups correctly into this scaffold and optimize the designed protein for life-like efficiency.

Indeed, the less ignorant we are, the less we have to depend on random search methods, and instead we can focus on more directed approaches. However, how this argument supports ID or can even be argued to be ID friendly is beyond me because ID depends on our ignorance to make its claims. Anytime science improves our understanding, Intelligent Design has lost another gap in which to hide.

Evolution’s intelligent designers

The article also touches on the concept of evolvability, another destroyer of ID gaps since evolvability itself can be shown to be under evolutionary control. In other words, while a simplistic argument based on the No Free Lunch theorems may argue that evolutionary mechanisms can never outperform a random search, reality is that evolvability makes the fitness landscape far from totally random. That evolution has been so successful can quickly be understood by understanding how evolutionary processes themselves can evolve.

Bloom et al. (2006) recently demonstrated that the stability of the protein scaffold improves its evolvability. In other words, when the stability of a protein scaffold is
increased, it may be possible to make mutations that create a truly novel property, which without increased stability would be too harmful for the protein. This approach can be very promising in finding novel enzymatic solutions that otherwise cannot be detected in the functional screening.

ID’s resident part-time ‘scientist’ and Friend Of Charles Darwin, Salvador Cordova (YEC) proudly proclaims the ‘good news’

Well by golly it seems there’s empirical evidence Darwinism doesn’t work so well in the very areas it hopes for vindication.

Amazing how abstract mining can lead to so much ignorance. What is even more amazing is how ID proponents seem to do anything but critically analyzing the arguments. To many of us that does not really come as a surprise.

As far as Dembski is concerned, he should really stick to what he knows best, or at last where his heart lies.

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Comment #168945

Posted by David B. Benson on April 9, 2007 7:31 PM (e)

PvM — That is a great title!

And is there anything that D*mbski knows best?

Comment #168948

Posted by Doc Bill on April 9, 2007 7:35 PM (e)

Dembski has become irrelevant to ID. Behe didn’t help at Kitzmiller by testifying under oath that ID wasn’t science and couldn’t be tested.

But prior to that Dembski’s influence was on the wane. I think Dembski is more worried about getting a steady paycheck teaching Christian apologetics at his bible college than he is about ID. Uncommon Descent into Madness is a huge embarrassment. I can only imagine that Dembski’s masters want to extract him from the insanity of the rabid DaveScot and What’s Her Name (buy my book) who spouts inanity like a demented lawn sprinkler.

Dembski is washed out and washed up. Has been. The Alfred E. Newman of Information. What, me worry?

Behe killed ID at Kitzmiller and Dembski didn’t even have the courage to attend the funeral.

Comment #168957

Posted by Mike Elzinga on April 9, 2007 8:35 PM (e)

Did you notice the wailing, self-pity that tyharris and his responders have been wallowing in on Uncommon Stench?

We are such horrible, unfair, cruel, cowardly “Darwinists”. I guess we don’t coddle enough in science. Horrors, we demand evidence, and we expect contributors to the scientific process to be accountable and know what the issues are and to not distort.

We even come down hard of fraudulent research. How can these poor creatures even get the adulation they so desperately want (without earning it)?

No violins, please; just kazoos and snare drums.

Comment #168959

Posted by Vyoma on April 9, 2007 9:49 PM (e)

This is a fine example of the extent to which the leaders of ID are willing to misdirect their followers and, worse, the degree to which those followers are willing to be misled. It’s no big deal to actually investigate what’s being said by reading the paper in question for oneself rather than relying on a second-hand account of what the paper says. The leaders are counting on the true-believers not to do this, however, and so essentially are trading on their followers being suckers, pure and simple, and that they will choose to be credulous.

I would like to believe that these people, who are simply being lied to by con-men who prey upon their ignorance, would choose to use this instance as motivation to stop being believers and start being investigators. I’d like to, but they probably won’t. That’s too bad; the explanatory power of science relies not on being told what to think, but precisely upon being skeptical to the degree that one analyzes a given claim — even one as simple as the one made by Dembski.

When I want more information about the content of a paper, I often write to its author, a simple thing that yielded important corroboration of an obsevration in a study I’m just finishing up currently. I wonder, does it occur to the “intelligent creationism” believers to do the same thing when they don’t even take it upon themselves to read the paper in the first place?

How does one learn anything without being intellectually curious about it in the first place?

Comment #168969

Posted by PvM on April 9, 2007 11:49 PM (e)

Yes, UcD has shown what happens when ‘science’ is abandoned for faith. Whether it be the vacuous scientific claims about ID or the ill informed ideas about global warming, it should become clear to anyone how ID proponents lack of scientific rigor and understanding leads them to accept poorly formulated concepts and doubt mainstream scientific findings.

What they fail to understand that in their eagerness to take down science, they are destroying both science and faith.

Comment #168993

Posted by Advocatus Diaboli on April 10, 2007 3:32 AM (e)

Well, the paper is written by Matti Leisola. He is the one and only prominent IDeist in Finland. Perhaps that explains Dembski’s enthusiasm to interpret the paper as pro-ID?

Comment #169031

Posted by kay on April 10, 2007 9:13 AM (e)

I think by now the whole ID thing is pro-forma… the next creo push will be to pimp out private (fundie) education through vouchers and homeschooling, and put community pressure on science teachers to skip the topic entirely.

Comment #169069

Posted by harold on April 10, 2007 2:36 PM (e)

I don’t know whether to be sad that they have creationists in Finland, or overjoyed that this country isn’t the only bastion of embarrassment.

I don’t know what would motivate a Finnish IDiot. Here, it’s all politics, not “faith”, politics.

ID was trumped up to reflect US politics. The authoritarian right wing wanted to pander to fundamentalists, first of all to get their votes, and second of all to advance the idea that harsh authoritarian policies can be supported by a few out-of-context “literally interpreted” harsh Biblical verses (but the desire for harsh policies drives the claim of Biblical interpretation, not the other way around). They were also eager to discredit science generally because they were annoyed by its role in protecting the environment, protecting public health, and so on.

So they cobbled up ID to “court-proof” creationism in schools.

There’s nothing spontaneous, faithful, or sincere about it, as the Wedge Document has been making clear since 1995.

Its appeal outside of the US and a few socially similar Anglophone countries like the UK, Canada, and Australia is odd.

Comment #169196

Posted by Torbjörn Larsson on April 11, 2007 6:26 AM (e)

harold wrote:

I don’t know what would motivate a Finnish IDiot.

There is always the odd nutjob in any sufficiently large population.

But we have fundamentalists in Europe as well, even eastern Europe including parts of Russia.

European christ-democratic parties contains and empower some of these anti-science fundamentalists. And there seems to be several creationist organizations in each country.

I’m not sure if anyone has kept track of their growth, if any.

Comment #169243

Posted by wamba on April 11, 2007 10:13 AM (e)

However, we still do not have a general theory on how to specify a structure that is suited to a target function nor can we specify a sequence that folds to a target structure. There is also overreliance on the Darwinian blind search to obtain practical results.

That’s kind of dumb. If you have no alternative that works, how can your use of the only method that does work be characterized as “overreliance”?